Finite element simulation of dispersion in the Bay of Santander

Two mathematical models are used to simulate pollution in the Bay of Santander. The first is the hydrodynamic model that provides the velocity field and height of the water. The second gives the pollutant concentration field as a resultant. Both models are formulated in two-dimensional equations. Linear triangular finite elements are used in the Galerkin procedure for spatial discretization. A finite difference scheme is used for the time integration. At each time step the calculated results of the first model are input to the second model as field data. The efficiency and accuracy of the models are tested by their application to a simple illustrative example. Finally a case study in simulation of pollution evolution in the Bay of Santander is presente

Evolució de la condició física en jugadores d’handbol en les categories infantil, cadet i juvenil

En aquesta investigació s’analitza la condició física de 91 jugadores d’handbol, amb edats compreses entre els 13 i els 18 anys, distribuïdes en tres categories diferents, infantil (n = 30), cadet (n = 32) i juvenil (n = 29). La investigació té caràcter descriptiu i transversal. El principal objectiu és analitzar l’estructura condicional de les jugadores. Per a la valoració es va aplicar la bateria Eurofit, la bateria de Bosco i test d’Abalakov. Es van trobar diferències significatives entre la categoria infantil-cadet en cinc de les 14 variables estudiades, i cap entre la categoria cadet-juvenil. Els millors resultats es van produir en la categoria juvenil. En general, les restants variables sempre van assolir millors valors que la població escolar (en aquelles variables en les quals la comparança va ser possible), però pitjors que els valors presentats per les jugadores de les seleccions espanyoles. En les proves que van valorar la força del tren inferior, els resultats indiquen que a major categoria les diferències són menors entre categories

Evolución de la condición física en jugadoras de balonmano en las categorías infantil, cadete y juvenil

En la presente investigación se analiza la condición física de 91 jugadoras de balonmano, con edades comprendidas entre 13 y 18 años, distribuidas en tres categorías diferentes, infantil (n = 30), cadete (n = 32) y juvenil (n = 29). La investigación tiene carácter descriptivo y transversal. El principal objetivo es analizar la estructura condicional de las jugadoras. Para su valoración se aplicó la batería Eurofit, la batería de Bosco y test de Abalakov. Se encontraron diferencias significativas entre la categoría infantil-cadete en cinco de las 14 variables estudiadas, y ninguna entre la categoría cadete-juvenil. Los mejores resultados se produjeron en la categoría juvenil. En general, las restantes variables siempre alcanzaron mejores valores que la población escolar (en aquellas variables en las que la comparación fue posible), pero peores que los valores presentados por las jugadoras de las selecciones españolas. En las pruebas que valoraron la fuerza de tren inferior, los resultados indican que a mayor categoría las diferencias son menores entre categorías

Problemes orals en un grup de nens amb leucèmia limfoblàstica aguda

La leucèmia limfoblàstica aguda (LLA) és principalment una malaltia infantil, les manifestacions bucals de la qual són molt importants per la seva alta incidència i també perquè poden constituir la primera localització ostensible de la malaltia. S'ha dut a terme un estudi sobre un grup d'onze pacients del Servei d'Hematooncologia de l'Hospital Universitari Materno-Infantil Vall d'Hebron de Barcelona, afectats per LLA, realitzant un examen oral en el qual es presta atenció especial a les lesions relacionades amb la LLA o amb el tractament que rebien els pacients. L'edat deis pacients oscil·la entre els 2 i els 14 anys i l'estat de la malaltia va des de LLA recentment diagnosticades i en tractament de quimioteràpia d'inducció fins a pacients no hospitalitzats en els quals ja s'havia suprimit el tractament. Fer notar la inexistència de casos amb simptomatologia oral molt florida degut a les extenses cures que reben els pacients al Servei d'Hematooncologia i a l'excel·lent programa preventiu establert per a ells, que inclou la profilaxi antifúngica i de mucositis. Es destaquen d'entre els signes la pal·lidesa oral, úlceres i lesions hemàtiques tipus equimosi i petèquies

Density-Dependent Prevalence of Francisella tularensis in Fluctuating Vole Populations, Northwestern Spain

Self Archiving; https://wwwnc.cdc.gov/eid/page/copyright-and-disclaimers J.J.L.L., F.M., and R.R.P. held official licenses for trapping wildlife in Spain. Capture permits were provided by the Dirección General del Medio Natural, Junta de Castilla y León. This study was supported by projects ECOVOLE (grant CGL2012-35348), ECOTULA (grant CGL2015-66962-C2-1-R), and RESERTULA (grant CLG2015-66962-C2-2-R), which were funded by the Ministerio de Economía y Competitividad MINECO/FEDER, Spain. R.R.P. was supported by a PhD studentship from the University of Valladolid (co-funded by Banco Santander).Peer reviewedPublisher PD

Molecular Determinants for the Activation/Inhibition of Bak Protein by BH3 Peptides

Apoptosis is a key procedure for all cells. Understanding this process and its regulation has been a subject of study in the last decades. Bcl-2 family of proteins are involved in the regulation of the apoptosis through the formation of homodimers or heterodimers between anti-apoptotic and pro-apoptotic proteins. Deregulation of pro-apoptotic proteins contributes to the progression of many tumour processes. Understanding how these proteins are activated is key to find new anti-cancer treatments. As no drug capable of activating Bak has been discovered yet, studying the structural and energetic insights of the binding of the known Bak activators, BH3 peptides, is essential to design new small molecules that resemble their binding to Bak. Recently, a BH3 Bim analogue has been discovered which inactivates Bak instead of activating it. Therefore, the present work is aimed to identify how BH3 peptides activate or inactivate Bak and determine any difference between them. Determination of the structural differences between the complexes with the activator and the inhibitor has been carried out by means of the study of the fluctuations of the corresponding Principal Components. Moreover, to calculate the binding free energy of the different complexes and to determine which residues of the peptide have the largest contribution to complex formation, MMPB/GBSA approaches are used. Results obtained in this work show differences in complexes with the activator and the inhibitor in structural and energetic terms, which can be used in the design of new molecules that could activate or inactivate pro-apoptotic Bak

Helminth communities of the exotic introduced turtle, Trachemys scripta elegans in southwestern Spain: Transmission from native turtles

We report the prevalence and diversity of helminth parasites found in native turtles Mauremys leprosa and Emys orbicularis from three localities in southwestern Spain and we describe the helminth communities of exotic turtles Trachemys scripta elegans coexisting in the wild with both native turtle species. Five nematodes species were identified, of which Serpinema microcephalus was the only species common between two localities, although infection parameters were different between them. This is the first report of cross transmission of S. microcephalus and Falcaustra donanaensis from native to exotic turtles and the first report of genus Physaloptera in turtles of the Palearctic Region. Continuous releasing of exotic pet turtles in wildlife ecosystems increases the risk of parasite introductions and, consequently, potential transmission to native species, and highlights the impending need for regulation of pet turtle trade in Europe

A CTMC-based characterisation of the propagation of errors in GMPLS Optical Rings

Abstract: This article presents a Continuous-Time Markov Chain model to characterise the propagation of failures in optical GMPLS rings. In order to characterize the behaviour of failure propagation epidemic-based models are commonly used. However, the existing epidemic models do not take into account the specific features of a multilayer network environment. A node failure in GMPLS-based networks can affect: Control Plane and Data plane reporting different failures scenarios. Consequently, an extended generic epidemic model called SID is proposed, in order to cover multiple failures and recovered states in a GMPLS Multilayer scenario. The CTMC model takes into account the SID model and provides a set of design rules to specify the values of repair rates required to achieve a given service availability, assuming a certain infection and disable rate.The work described in this paper was carried out with the support of the BONE project (''Building the Future Optical Network in Europe''), a Network of Excellence funded by the European Commission through the 7th ICT-Framework Programme. Additionally, the authors would like to thank the support of the T2C2 Spanish project (under code TIN2008-06739-C04-01) and the Madrid Community through the MEDIANET project (S-2009/TIC-1468) to the development of this work. This work is partially supported by Spanish Ministry of Science and Innovation project TEC 2009-10724 and by Generalitat de Catalunya research support program (SGR-1202).Publicad

Composición y estructura de la ictiofauna del río Hondo, México-Belice, con base en el uso del arpón

ResumenSe determinó la composición y estructura de la ictiofauna del río Hondo y la variación espacial de éstas en función de los parámetros ambientales. Se realizaron 3 muestreos durante marzo, abril y mayo de 2012, en 6 sitios a lo largo del río. Los datos usados para determinar la estructura se obtuvieron con ayuda de un arpón de 58.5cm, utilizado durante 2h de buceo libre en cada punto de muestreo. Para complementar la lista de especies se utilizaron redes agalleras, palangres, nasas y anzuelos. Además, se realizó una revisión bibliográfica y se consultó material de la colección de peces de ECOSUR en Chetumal. La lista sistemática se conformó por 40 especies en 33 géneros, 18 familias y 11 órdenes. La familia mejor representada fue Cichlidae, incluida la especie exótica Oreochromis niloticus. Los parámetros ambientales que mejor describieron la variación de la distribución y abundancia en los peces en el río Hondo fueron: la anchura del río, distancia a la boca, transparencia, profundidad, concentración de oxígeno disuelto y conductividad. La relación entre las especies y las variables ambientales fue alta en ambos ejes (0.89 y 0.79). Ambientalmente, el río se puede zonificar en 3 partes, aunque su ictiofauna puede dividirse en 2 conjuntos principales.AbstractComposition and structure of the Hondo River ichthyofauna and its spatial variation were determined as a function of environmental parameters. Six sites along the river were sampled in March, April and May 2012. Data for estimating structure of fish assemblages was obtained by means of a 58.5cm harpoon during 2 hours of free diving at each sampling site. The species list for the study area was completed with the aid of gillnets, longlines, double-cone traps, and hook-and-line. In addition, a bibliographical research performed as well as the ichthyological collection of ECOSUR at Chetumal was checked. The systematic list includes 40 species in 33 genera, 18 families and 11 orders. The richest family was Cichlidae, including the exotic Oreochromis niloticus. The environmental parameters that best described distribution and abundance of fish in the Hondo River were river width, distance to mouth, transparency, depth, dissolved oxygen concentration, and conductivity. Correlation between species and environmental parameters was high in both axis (0.89 and 0.79). The river was classified into 3 environmental zones, although its fish fauna could be divided in 2 main assemblages